Fungivorous amoebae as a novel biofungicide

The image shows test tubes lined up, each containing an orange liquid.
Laboratory cultures of fungivorous amoebae (source: F. Hillmann)

Bioprocess engineering research on amoeboid microorganisms for the development of sustainable crop protection strategies and novel biotechnological applications

AMOEBOFUN is developing a novel biological crop protection product against harmful fungi. It is based on naturally occurring fungus-feeding microorganisms from the group Amoebozoa that live on leaf surfaces and are harmless to humans, animals, and plants. These amoebae feed on fungi and are intended to help reduce plant diseases in agriculture and horticulture in an environmentally friendly way.

The aim of the project is to produce resistant dormant forms of the amoebae in large quantities and process them into a storable powder product. This powder is intended to be mixed with water and applied to plants using conventional spraying equipment. This could reduce the use of chemical fungicides. At the same time, the approach offers a new way to prevent resistance to conventional products and to better meet environmental regulations. Especially in organic farming, it could help reduce the use of copper-based products.

Initial trials have already shown promising results for apple scab, fungal infections in wheat, and successful establishment on potato surfaces. The project will now further improve production, formulation, and application. In addition, important data for future regulatory approval in Germany and the EU will be generated.

The consortium combines the research expertise of Hochschule Wismar with the industrial experience of e-nema GmbH. Together, they aim to develop a marketable biological alternative to chemical fungicides. AMOEBOFUN therefore contributes to more sustainable, resilient, and biodiversity-friendly agriculture.


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